ABSTRACT
Pulmonary hypertension (PH) is a common complication in patients with end-stage renal disease (ESRD), especially in patients with hemodialysis (HD). Poor prognosis can eventually lead to right heart failure and even death. PH is an independent risk factor for increased mortality in ESRD patients. We should pay attention to these patients in clinic for early detection, prevention and treatment. The pathogenesis of PH in ESRD patients is still unclear so far, which might be related to the increase of pulmonary vascular resistance, pulmonary blood flow, and pulmonary arterial wedge pressure. In addition, the presence of risk factors can promote the development of PH, such as chronic hypoxia, vascular calcification, and inflammation.
Subject(s)
Humans , Heart Failure , Hypertension, Pulmonary , Kidney Failure, Chronic , Renal Dialysis , Risk FactorsABSTRACT
Pulmonary veno-occlusive disease (PVOD)/pulmonary capillary hemangiomatosis (PCH) is a rare form of pulmonary vascular disease that causes pulmonary arterial hypertension.The diagnosis of PVOD/PCH can be established by the combination of clinical features,physical examination,radiological findings,lung function,bronchoscopy and other resources.There is no established medical therapy for PVOD/PCH,and the only curative therapy for PVOD/PCH is lung transplantation.A girl with PVOD/PCH was diagnosed in the Second Xiangya Hospital.Combining the characteristics for this case with the relevant literature,we summarized the epidemiology,etiology,diagnosis and treatment for the disease to raise doctors' awareness for this rare disease.